“New Study Explores Best Ways to Safely Reduce Prednisone After NMDAR Encephalitis Treatment”

Deep brain stimulation (DBS) is gaining attention as a possible treatment for drug-resistant epilepsy (DRE), a condition where traditional medications just don’t cut it. One innovative approach involves low-frequency stimulation (LFS) targeting specific brain fiber tracts, like the corpus callosum (CC). This method seems to work by suppressing seizure activity across the cortex, but the exact ways it achieves this were still a bit of a mystery.

Researchers are diving into the potential of exogenous ketones—compounds that can help produce ketones in the body—as a treatment for epilepsy, with a particular focus on how they might affect seizures and the gut microbiome. This study explored how administering a ketone ester (KE) through two different methods—oral gavage (basically, feeding it to the mice) and subcutaneous (SC) injection (like getting a shot)—influences seizure activity in mice that model aspects of human temporal lobe epilepsy.

Traumatic brain injuries (TBI) can lead to various complications, including seizures, which can be either functional (non-epileptic) or epileptic. Unfortunately, treatments for these seizure conditions in TBI patients are limited, prompting researchers to explore the effectiveness of a specific therapy called neurobehavioral therapy (NBT). In a new study, scientists looked into how well NBT worked for patients dealing with both TBI and seizures over the course of a year.

Epilepsy is a common brain condition that affects millions, but for about one-third of those with it, traditional medications just don’t work, leading to what’s called drug-resistant epilepsy (DRE). This situation calls for new treatment options, and researchers are looking into a technique known as transcranial magnetic continuous theta burst stimulation (cTBS). In a recent clinical trial, scientists set out to see if this method could effectively treat DRE by specifically targeting an area of the brain called the cerebellum.

Researchers have recently made significant strides in understanding how to potentially prevent epilepsy following a severe brain condition called status epilepticus (SE). SE is characterized by prolonged, uncontrolled seizures and leads to brain changes that can trigger epilepsy later on. A critical aspect of this study involved examining the role of the glymphatic system, which…

In a recent study, researchers investigated the antiseizure effects of three compounds—amorfrutin 2, honokiol, and magnolol—that have a similar structure to cannabinoids but come from non-cannabis plants.