Cenobamate May Help Reduce Seizures in Epilepsy Patients

Source: Epilepsia open

Summary

A study was conducted to look at how effective Cenobamate (CNB) is for adults with idiopathic generalized epilepsy (IGE), a type of epilepsy that can be hard to treat. The researchers reviewed medical records from a large healthcare system and focused on 16 adults, most of whom had juvenile myoclonic epilepsy and had tried many other treatments without success. They tracked how often patients had seizures and how long they continued taking CNB over a year.

The results showed that more than half of the patients (57%) were able to keep taking CNB for at least 12 months. Many patients experienced a significant reduction in seizures, with 75% seeing at least a 50% decrease in seizures after 3 months, and 63% still experiencing this reduction after a year. Additionally, the number of emergency room visits dropped significantly after starting CNB. However, some patients reported side effects like fatigue, dizziness, and cognitive issues.

These findings are important because they suggest that Cenobamate may be a helpful option for adults with IGE who have not responded well to other treatments. However, this study had a small number of participants and was conducted at a single center, so more research is needed to confirm these results and understand the long-term effects of CNB.

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