Corpus Callosotomy in LGS: Seizure Outcomes and Evidence Limits
Researchers combined results from 48 studies involving 822 people with Lennox-Gastaut syndrome across 19 countries.
This hub covers epilepsy devices and neuromodulation like VNS, RNS, and DBS, which are treatments that can reduce seizures when meds arenβt enough. Plain-language research summaries plus real-life pros/cons.
Some are used more often in adults, but pediatric use depends on the device, the case, and specialist guidance.
Often gradually. Improvement can build over months as settings are optimized.
Sometimes medication can be reduced, but many people still use meds alongside a device.
Sometimes yes, with device-specific rules. Always check the exact device guidelines first.
Researchers combined results from 48 studies involving 822 people with Lennox-Gastaut syndrome across 19 countries.
This systematic review and meta-analysis examined neuromodulation treatments for people younger than 18 years with drug-resistant epilepsy.
This article was a critical review, not a new clinical trial, and the abstract does not report enrolling participants.
This systematic review examined published reports from January 1990 through April 2025 involving people of any age whose seizures returned after hemispheric disconnection surgery, also called hemispherectomy or hemispherotomy.
This study looked at whether a computer system could find very fast brain wave patterns called high-frequency oscillations, or HFOs, during epilepsy surgery.
This study looked at thalamic neuromodulation for children with drug-resistant epilepsy, meaning epilepsy that did not respond well to medicines.
This study looked at whether brain PET scan templates made for children, and matched to different ages, can help improve localization of the epileptogenic zone, the brain area where seizures start, in children with drug-resistant epilepsy.
This paper reviewed published studies on using perampanel alone (monotherapy) in children with epilepsy.
This paper is a review, not a new experiment.