Clobazam Shows Promise for Children with Uncontrolled Seizures
Source: Epilepsy & behavior : E&B
Summary
A study was conducted to evaluate how effective and safe clobazam (CLB) is when added to treatment for children with epilepsy who did not respond well to their first medication. This analysis focused on 107 children under 18 years old from a larger study called the ADD-ON study, which took place in 28 outpatient clinics in India. The children had been experiencing seizures for an average of two years, and most had tonic-clonic seizures, which are a common type of seizure.
The results showed that after one year of taking clobazam, about 69% of the children were seizure-free. This means that clobazam was effective for many of the kids who had not found relief with their previous medication. Additionally, the study did not report any major side effects related to clobazam, suggesting that it was well-tolerated by the children who participated.
These findings are important because they indicate that clobazam can be a helpful option for children with epilepsy who need additional treatment after their first medication fails. However, itβs important to note that this study was not a controlled trial, so further research is needed to confirm these results and understand how clobazam works in different situations.
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