New Trial Aims to Improve Rehabilitation for Young Stroke Survivors
⚠️ Infant dosing/safety: medication and diet decisions for infants require individualized medical guidance.
Source: Stroke
Summary
The I-ACQUIRE Phase 3 trial studied infants and toddlers aged 8 to 36 months who had experienced perinatal arterial ischemic stroke, which can lead to movement difficulties and other disabilities. The trial involved 216 children, with 168 completing the necessary assessments. Researchers wanted to see if a specific rehabilitation program, called I-ACQUIRE, could help improve motor skills compared to usual treatments. The program included different levels of intensity, with some children receiving more hours of therapy than others.
The key findings of the study will be determined by comparing the motor skills of children who received the I-ACQUIRE therapy to those who received standard care. The researchers will look for improvements in the use of the affected arm and hand, as well as overall motor skills. They will assess these changes at the end of the treatment and again six months later. The trial aims to see if either of the I-ACQUIRE treatment levels leads to significant improvements in these skills.
This study is important because it could help identify effective rehabilitation strategies for young children with movement challenges after a stroke. If the I-ACQUIRE program shows positive results, it may guide future treatment decisions for families and healthcare providers. However, the trial has limitations, such as the specific age range and the fact that many participants had seizures or epilepsy, which could affect the results.
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