This hub covers epilepsy genetics: how gene changes can contribute to seizures (often in children). We translate studies on testing, results like VUS, and what findings may change for care.
No. It’s common in pediatrics, but adults can benefit from genetic testing, too, especially with unclear diagnosis or family history.
Sometimes. For certain conditions, results can guide medication choice, diet therapies, or referral decisions.
It usually means “not enough evidence yet.” It shouldn’t be treated as a definite cause, but it can be reclassified over time.
Not necessarily. Testing can miss some variants, and new gene links are still being discovered.
Researchers studied the outcomes of pediatric epilepsy surgery by examining data from 100 procedures performed on 62 children and young adults.
This study looked at children aged 1 month to 18 years who experienced status epilepticus (SE), a serious condition where seizures last too long or occur back-to-back without recovery in between.
This study looked at how effective and safe the ketogenic diet therapy (KDT) is for infants under two years old who have epilepsy that does not respond to medications.
This study looked at children born to women with epilepsy to see if they have a higher genetic risk for neurodevelopmental disorders, like ADHD and autism, compared to children whose mothers do not have epilepsy.
This study looked at how often psychiatric disorders, like depression and anxiety, occur alongside neurological disorders, such as epilepsy and multiple sclerosis.
Researchers studied the relationship between cerebral radiation necrosis (CRN) and epilepsy in patients who have undergone radiation therapy.
Researchers studied how well different animal models can predict the effectiveness of antiseizure medications (ASMs) for people with focal drug-resistant epilepsy (DRE).
This study looked at 177 children with epilepsy and specific genetic changes called copy number variants (CNVs).
Researchers studied infants aged 1 to 24 months who experienced their first seizure without fever or were newly diagnosed with epilepsy.