This hub covers drug-resistant epilepsy: When seizures aren’t controlled after trying two appropriate medicines. Research-backed next steps on diet therapies, devices, surgery evaluation, and safety.
If seizures aren’t controlled after two meds, it’s worth at least an evaluation at an epilepsy center.
Not necessarily. Some familiar consider it earlier depending on seizure type and goals.
Yes. Treatment response can change over time, and combinations/approaches matter.
Seizure frequency, triggers, sleep, missed meds, side effects, and rescue med use.
This study looked at five adults with Febrile Infection-Related Epilepsy Syndrome (FIRES), a serious condition that causes severe seizures after a fever.
Researchers studied how different parts of the brain work together during speech tasks, focusing on patients with drug-resistant epilepsy who were preparing for surgery.
Researchers studied deep brain stimulation (DBS) as a treatment for people with epilepsy who do not respond to medications and cannot have surgery to remove the affected brain tissue.
Researchers studied two children with a rare type of epilepsy caused by changes in the WWOX gene.
This study looked at how two treatments, vagus nerve stimulation (VNS) and epilepsy surgery (ES), affect the use of seizure medications in children with drug-resistant epilepsy (DRE).
This study focused on children with drug-resistant epilepsy, which means their seizures do not respond well to standard medications.
Researchers studied deep brain stimulation (DBS) as a treatment for people with epilepsy who do not respond to medications and cannot have surgery to remove the affected brain tissue.
This study looked at how well three different neuromodulation techniques—Vagus Nerve Stimulation (VNS), Responsive Neurostimulation (RNS), and Deep Brain Stimulation (DBS)—work for adults with refractory bitemporal lobe epilepsy (BTLE), which is a type of epilepsy that is hard to treat…
This study focuses on the use of vagus nerve stimulation (VNS) as a treatment for status epilepticus in children, which is a serious condition where seizures last too long or happen back-to-back.