This hub covers drug-resistant epilepsy: When seizures aren’t controlled after trying two appropriate medicines. Research-backed next steps on diet therapies, devices, surgery evaluation, and safety.
If seizures aren’t controlled after two meds, it’s worth at least an evaluation at an epilepsy center.
Not necessarily. Some familiar consider it earlier depending on seizure type and goals.
Yes. Treatment response can change over time, and combinations/approaches matter.
Seizure frequency, triggers, sleep, missed meds, side effects, and rescue med use.
Researchers studied children with severe epilepsy who underwent a procedure called hemispherectomy, where one side of the brain is removed or disconnected to control seizures.
Researchers studied the use of right vagal nerve stimulation (R-VNS) as a treatment for epilepsy, focusing on patients who had not responded well to other therapies.
This study focused on the effects of brain surgery for people with epilepsy caused by a condition called polymicrogyria (PMG).
A study was conducted to look at how effective vagus nerve stimulation (VNS) is for treating children with hard-to-control epilepsy, specifically those who have myoclonic seizures.
This study looked at the effects of highly purified cannabidiol (CBD) on girls with CDKL5 deficiency disorder (CDD), a condition that causes severe seizures and other challenges.
Researchers studied how the ketogenic diet (KD) affects the microbiota-gut-brain axis (MGBA) in people with drug-resistant epilepsy (DRE).
Researchers studied a patient with unusual movement problems linked to a change in the PRRT2 gene.
This study looked at how effective and safe four different medications—brivaracetam, cenobamate, lacosamide, and perampanel—are for adults with drug-resistant focal epilepsy.
Researchers studied how children with movement disorders, specifically those with severe muscle stiffness (known as hypertonia), are evaluated before undergoing neurosurgery.