This hub covers drug-resistant epilepsy: When seizures aren’t controlled after trying two appropriate medicines. Research-backed next steps on diet therapies, devices, surgery evaluation, and safety.
If seizures aren’t controlled after two meds, it’s worth at least an evaluation at an epilepsy center.
Not necessarily. Some familiar consider it earlier depending on seizure type and goals.
Yes. Treatment response can change over time, and combinations/approaches matter.
Seizure frequency, triggers, sleep, missed meds, side effects, and rescue med use.
This study looked at how effective and safe the ketogenic diet therapy (KDT) is for infants under two years old who have epilepsy that does not respond to medications.
Researchers studied how weather conditions, like atmospheric pressure, temperature, and humidity, affect the number of seizures in children with drug-resistant epilepsy (DRE).
This study looked at the effects of deep brain stimulation (DBS) on adults with drug-resistant epilepsy (DRE) who had not found relief from other treatments, including vagus nerve stimulation (VNS).
Researchers studied how well different animal models can predict the effectiveness of antiseizure medications (ASMs) for people with focal drug-resistant epilepsy (DRE).
Researchers studied 155 patients with drug-resistant focal epilepsy to see if a specific brain imaging method could help predict how well they would respond to a medication called lacosamide (LCM).
Researchers studied how different parts of the brain communicate in patients with epilepsy, focusing on the areas where seizures start, known as the seizure onset zone (SOZ).
This study looked at patients who started having seizures for the first time during a COVID-19 infection.
Researchers studied the effects of a treatment called Liposom Forte, which contains hypothalamic phospholipids, in three patients with different neurological disorders.
Researchers studied how brain networks are affected in people with nonlesional focal epilepsy, which is a type of epilepsy that doesn’t show visible brain damage on scans.