This hub covers drug-resistant epilepsy: When seizures aren’t controlled after trying two appropriate medicines. Research-backed next steps on diet therapies, devices, surgery evaluation, and safety.
If seizures aren’t controlled after two meds, it’s worth at least an evaluation at an epilepsy center.
Not necessarily. Some familiar consider it earlier depending on seizure type and goals.
Yes. Treatment response can change over time, and combinations/approaches matter.
Seizure frequency, triggers, sleep, missed meds, side effects, and rescue med use.
This systematic review and meta-analysis examined neuromodulation treatments for people younger than 18 years with drug-resistant epilepsy.
Researchers studied how often children were not recommended for epilepsy surgery and whether recommendations differed among epilepsy centers.
This systematic review examined medium-chain triglyceride (MCT)-based interventions for people with drug-resistant epilepsy.
This article was a critical review, not a new clinical trial, and the abstract does not report enrolling participants.
This narrative review brought together published research on early infantile developmental and epileptic encephalopathy (EIDEE), a severe epilepsy syndrome beginning before 3 months of age.
This scoping review mapped published research on epilepsy of infancy with migrating focal seizures (EIMFS), a rare and severe epilepsy syndrome beginning in infancy.
The provided source contains only publication details for an article in Epilepsia Open.
This hospital-based study looked at 136 children with developmental and epileptic encephalopathies (DEEs).
This study looked at whether computer models built from seizure-free brain recordings could help identify vulnerable parts of the brain network involved in seizure onset during presurgical evaluation for drug-resistant epilepsy.