This hub covers epilepsy genetics: how gene changes can contribute to seizures (often in children). We translate studies on testing, results like VUS, and what findings may change for care.
No. It’s common in pediatrics, but adults can benefit from genetic testing, too, especially with unclear diagnosis or family history.
Sometimes. For certain conditions, results can guide medication choice, diet therapies, or referral decisions.
It usually means “not enough evidence yet.” It shouldn’t be treated as a definite cause, but it can be reclassified over time.
Not necessarily. Testing can miss some variants, and new gene links are still being discovered.
This article was a critical review, not a new clinical trial, and the abstract does not report enrolling participants.
This narrative review brought together published research on early infantile developmental and epileptic encephalopathy (EIDEE), a severe epilepsy syndrome beginning before 3 months of age.
This scoping review mapped published research on epilepsy of infancy with migrating focal seizures (EIMFS), a rare and severe epilepsy syndrome beginning in infancy.
Researchers combined 50 observational studies involving 10,743 people who presented with seizures in South-East Asia.
Researchers described co-occurring health conditions in 1,054 children and youth with validated epilepsy diagnoses in Norway.
This hospital-based study looked at 136 children with developmental and epileptic encephalopathies (DEEs).
This report describes one child: a 12-year-old girl who presented at age 11 with daily absence seizures that did not respond to multiple antiseizure medicines.
This study looked at thalamic neuromodulation for children with drug-resistant epilepsy, meaning epilepsy that did not respond well to medicines.
This paper is a review, not a new experiment.