This hub covers drug-resistant epilepsy: When seizures aren’t controlled after trying two appropriate medicines. Research-backed next steps on diet therapies, devices, surgery evaluation, and safety.
If seizures aren’t controlled after two meds, it’s worth at least an evaluation at an epilepsy center.
Not necessarily. Some familiar consider it earlier depending on seizure type and goals.
Yes. Treatment response can change over time, and combinations/approaches matter.
Seizure frequency, triggers, sleep, missed meds, side effects, and rescue med use.
Researchers studied the use of cannabidiol, a compound found in cannabis, in children with developmental and epileptic encephalopathies (DEEs).
Researchers studied 160 patients with absence seizures linked to specific genetic causes, known as monogenic epilepsies.
Researchers studied how well machine learning could predict the effectiveness of anti-seizure medications (ASMs) using routine EEG tests.
Researchers studied the use of vigabatrin (VGB) as a preventive treatment for infants with tuberous sclerosis complex (TSC), a condition that often leads to early-onset epilepsy.
This study looked at a specific genetic cause of focal epilepsy called DEPDC5 variants, which are often linked to brain abnormalities.
Researchers studied the effects of Ivermectin (IVM) on patients with drug-resistant epilepsy, which means their seizures are hard to control even with multiple medications.
Researchers studied how deep brain stimulation (DBS) and responsive neurostimulation (RNS) can help people with drug-resistant epilepsy (DRE), which is epilepsy that doesn’t respond to medications.
This study looked at a group of Japanese patients with specific genetic changes known as DHDDS variants, which are linked to severe epilepsy and movement disorders.
This study looked at how two different surgical methods for treating drug-resistant mesial temporal lobe epilepsy affect thinking skills, particularly memory and naming abilities.