This hub covers drug-resistant epilepsy: When seizures aren’t controlled after trying two appropriate medicines. Research-backed next steps on diet therapies, devices, surgery evaluation, and safety.
If seizures aren’t controlled after two meds, it’s worth at least an evaluation at an epilepsy center.
Not necessarily. Some familiar consider it earlier depending on seizure type and goals.
Yes. Treatment response can change over time, and combinations/approaches matter.
Seizure frequency, triggers, sleep, missed meds, side effects, and rescue med use.
Researchers studied the effectiveness and safety of a medication called perampanel in patients with Lennox-Gastaut syndrome (LGS), a severe form of epilepsy that often starts in childhood.
This study looked at how certain brain activity signals, called biomarkers, can help predict how well invasive treatments for drug-resistant epilepsy (DRE) work.
Researchers studied the characteristics of epilepsy in patients with Muscle-Eye-Brain disease (MEB), a rare genetic condition that affects muscle and brain development.
Researchers studied a specific type of brain condition called focal cortical dysplasia type II (FCDII), which is a common cause of epilepsy in children that does not respond to medication.
This study looked at how effective and safe continuous midazolam (MDZ) infusion is for treating acute repetitive seizures and status epilepticus in children outside of intensive care settings.
Researchers studied a 5-year-old girl with a severe form of epilepsy called drug-resistant epilepsy (DRE) caused by a condition known as hemimegalencephaly, where one side of the brain is abnormally large.
Researchers studied how brain activity patterns might predict whether children with drug-resistant focal epilepsy would benefit from vagus nerve stimulation (VNS), a treatment option for epilepsy.
This study looked at the reasons why children with drug-resistant epilepsy (DRE) often experience delays in getting surgery that could help them.
This study looked at how well a method called intracranial electroencephalographic (iEEG) connectivity analysis can help locate the areas in the brain responsible for seizures in adults with focal drug-resistant epilepsy.