This hub covers drug-resistant epilepsy: When seizures aren’t controlled after trying two appropriate medicines. Research-backed next steps on diet therapies, devices, surgery evaluation, and safety.
If seizures aren’t controlled after two meds, it’s worth at least an evaluation at an epilepsy center.
Not necessarily. Some familiar consider it earlier depending on seizure type and goals.
Yes. Treatment response can change over time, and combinations/approaches matter.
Seizure frequency, triggers, sleep, missed meds, side effects, and rescue med use.
Researchers studied the use of cannabidiol (CBD) as an additional treatment for children over the age of 2 who have drug-resistant epileptic spasms (ES).
Researchers studied the use of nicotine as a treatment for Sleep-Related Hypermotor Epilepsy (SHE), a type of epilepsy that can have a genetic cause.
In this study, researchers looked at how sevoflurane anesthesia affects brain activity in children with drug-resistant focal epilepsy.
This study looked at the effects of a plant extract called Ammi visnaga, commonly known as the toothpick plant, on seizures in mice.
This study looked at pediatric epilepsy in Palestine, focusing on children aged 2 months to 18 years who were diagnosed between 2019 and 2024.
A study was conducted to evaluate the effectiveness and safety of a new medication called JNJ-40411813 when used alongside two existing epilepsy treatments, levetiracetam and brivaracetam.
This study looked at the occurrence of seizures and epilepsy in children diagnosed with leukodystrophies, which are rare brain disorders that affect the white matter of the brain.
Researchers studied a new tool called the iKETO-KNOW Questionnaire, which was designed to measure how much adult patients and caregivers know about the ketogenic diet therapy (KDT) for epilepsy.
Researchers studied the use of stereoelectroencephalography (SEEG) in patients with drug-resistant focal epilepsy.