This hub covers drug-resistant epilepsy: When seizures aren’t controlled after trying two appropriate medicines. Research-backed next steps on diet therapies, devices, surgery evaluation, and safety.
If seizures aren’t controlled after two meds, it’s worth at least an evaluation at an epilepsy center.
Not necessarily. Some familiar consider it earlier depending on seizure type and goals.
Yes. Treatment response can change over time, and combinations/approaches matter.
Seizure frequency, triggers, sleep, missed meds, side effects, and rescue med use.
This study focused on children with hemophagocytic lymphohistiocytosis (HLH), a serious condition that causes severe inflammation and can affect the brain.
Researchers studied the effectiveness of using common clinical characteristics to predict the results of genetic testing in adults with epilepsy.
Researchers studied early infantile epileptic encephalopathy (EIEE), a severe type of epilepsy that starts in infants and can lead to serious developmental issues.
Researchers studied the effects of a treatment called continuous hippocampal deep brain stimulation (Hip-DBS) on memory and cognitive function in patients with drug-resistant temporal lobe epilepsy (TLE).
Researchers studied new treatments for epilepsy, focusing on those currently being tested in clinical trials.
A recent study looked at the use of repetitive transcranial magnetic stimulation (rTMS) as an additional treatment for adults with drug-resistant epilepsy (DRE), which means their seizures do not respond well to standard medications.
Researchers studied a new treatment called epicranial focal cortex stimulation (eFCS) for people with epilepsy that does not respond to medication.
This study focused on a rare genetic disorder called cyclin-dependent kinase-like 5 deficiency (CDD), which leads to severe epilepsy and developmental challenges.
Researchers studied two diets, the classical ketogenic diet (CKD) and the modified Atkins diet (MAD), to see how well they help children with drug-resistant epilepsy (DRE).