This hub covers drug-resistant epilepsy: When seizures aren’t controlled after trying two appropriate medicines. Research-backed next steps on diet therapies, devices, surgery evaluation, and safety.
If seizures aren’t controlled after two meds, it’s worth at least an evaluation at an epilepsy center.
Not necessarily. Some familiar consider it earlier depending on seizure type and goals.
Yes. Treatment response can change over time, and combinations/approaches matter.
Seizure frequency, triggers, sleep, missed meds, side effects, and rescue med use.
This paper is a review about neurology-centered clinical management of Angelman syndrome, especially seizure care.
Researchers evaluated a brain device treatment called responsive thalamic stimulation as an add-on therapy for people with drug-resistant idiopathic generalized epilepsy (IGE) who had generalized tonic-clonic seizures (GTCSs).
This study looked at current pediatric epilepsy surgery and presurgical evaluation practices around the world.
This study looked at very early epilepsy surgery in infants 6 months old or younger who had severe epilepsy linked to structural brain problems present from birth.
This study looked at polymorphous low-grade neuroepithelial tumor of the young (PLNTY), a recently recognized brain tumor type linked with epilepsy.
This paper is a case report.
This study combined results from 12 earlier studies to estimate how common drug-resistant epilepsy is in low- and middle-income countries.
Researchers looked at whether turning vagus nerve stimulation (VNS) on or off changed brain blood flow-related measurements in people with drug-resistant epilepsy.
This paper was a systematic review, which means the authors gathered and summarized earlier studies rather than testing one new group of patients.