This hub covers epilepsy genetics: how gene changes can contribute to seizures (often in children). We translate studies on testing, results like VUS, and what findings may change for care.
No. It’s common in pediatrics, but adults can benefit from genetic testing, too, especially with unclear diagnosis or family history.
Sometimes. For certain conditions, results can guide medication choice, diet therapies, or referral decisions.
It usually means “not enough evidence yet.” It shouldn’t be treated as a definite cause, but it can be reclassified over time.
Not necessarily. Testing can miss some variants, and new gene links are still being discovered.
In a study involving 249 children who experienced new-onset bilateral tonic-clonic seizures, researchers aimed to understand how different diagnostic methods could help classify the type of seizures.
This study looked at the types and causes of seizures in cats and dogs.
This study looked at two types of epilepsy that can occur in infants: infantile epileptic spasms syndrome (IESS) and self-limited infantile epilepsy (SeLIE).
Researchers studied the connection between clock genes, which help regulate our body’s daily rhythms, and epilepsy.
Researchers studied deep brain stimulation (DBS) as a treatment for people with epilepsy who do not respond to medications and cannot have surgery to remove the affected brain tissue.
Researchers studied how to detect unusual patterns in heart and brain activity data, specifically using ECG (heart) and EEG (brain) readings.
Researchers studied the metabolic profiles of people with epilepsy to see if there are common patterns among different groups.
This study focuses on the use of vagus nerve stimulation (VNS) as a treatment for status epilepticus in children, which is a serious condition where seizures last too long or happen back-to-back.
Researchers studied how machine learning (ML) can help predict where seizures start in patients with drug-resistant epilepsy (DRE).