This hub covers epilepsy genetics: how gene changes can contribute to seizures (often in children). We translate studies on testing, results like VUS, and what findings may change for care.
No. It’s common in pediatrics, but adults can benefit from genetic testing, too, especially with unclear diagnosis or family history.
Sometimes. For certain conditions, results can guide medication choice, diet therapies, or referral decisions.
It usually means “not enough evidence yet.” It shouldn’t be treated as a definite cause, but it can be reclassified over time.
Not necessarily. Testing can miss some variants, and new gene links are still being discovered.
This study combined results from 14 research studies about COVID-19 vaccine hesitancy in adults with epilepsy.
This paper reviewed published studies about seizure emergencies in Spain.
This study looked at whether intravenous immunoglobulin, called IVIG, might help children with drug-resistant epilepsy.
This paper reviewed published research on monogenic developmental and epileptic encephalopathies (DEE), with a focus on movement disorders that occur along with epilepsy.
This paper combined results from 10 randomized controlled trials that tested educational programs for children with epilepsy and/or their parents or caregivers.
This study looked at which first antiseizure medicine was prescribed to children with epilepsy in the United States from 2015 to 2024.
This study looked at brivaracetam (BRV) used alone as the initial seizure medicine in patients with juvenile myoclonic epilepsy (JME).
This preliminary study looked at gut bacteria in children with infantile epileptic spasms syndrome (IESS), a severe epilepsy syndrome in infancy.
This exploratory pilot study looked at whether certain MRI features of a brain malformation called focal cortical dysplasia type II (FCD II) were linked with neuropsychological functioning in children and teens with pharmacoresistant epilepsy.