This hub covers epilepsy genetics: how gene changes can contribute to seizures (often in children). We translate studies on testing, results like VUS, and what findings may change for care.
No. It’s common in pediatrics, but adults can benefit from genetic testing, too, especially with unclear diagnosis or family history.
Sometimes. For certain conditions, results can guide medication choice, diet therapies, or referral decisions.
It usually means “not enough evidence yet.” It shouldn’t be treated as a definite cause, but it can be reclassified over time.
Not necessarily. Testing can miss some variants, and new gene links are still being discovered.
Researchers studied deep brain stimulation (DBS) as a treatment for people with epilepsy who do not respond to medication and cannot have surgery.
Researchers studied a genetic condition called CDKL5 deficiency disorder (CDD) using mice that lack the CDKL5 gene.
Researchers studied how well two different questionnaires, the Generalized Anxiety Disorder-2 (GAD-2) and the Generalized Anxiety Disorder-7 (GAD-7), can identify anxiety symptoms in children who have headaches or epilepsy.
Researchers studied different genetic changes in a specific part of the SCN1A gene, which is important for a protein that helps control electrical signals in the brain.
Researchers studied Dravet syndrome (DS), a severe form of epilepsy that begins in infancy and is often resistant to treatment.
Researchers studied the effects of ketogenic diets (KDs) on people with various health conditions, including epilepsy.
This study looked at the long-term effects of infantile epileptic spasms syndrome (IESS) in children in Korea.
A recent study looked at how fasting during Ramadan affects seizure activity in adults with epilepsy.
Researchers studied a method called transcranial magnetic stimulation (TMS) to see if it could be effectively timed to occur during specific brain activity known as interictal epileptiform discharges (IEDs).